Elastography of the bone-implant interface

Understanding and controlling the bone-implant interface.

A goal of current implantology research is to design devices that induce controlled, guided, and rapid healing. In addition to acceleration of normal wound healing phenomena, endosseous implants should result in formation of a characteristic interfacial layer and bone matrix with adequate biomechanical properties. To achieve these goals, however, a better understanding of events at the interfac...

Study of a new bone-targeting titanium implant–bone interface

New strategies involving bone-targeting titanium (Ti) implant-bone interface are required to enhance bone regeneration and osseointegration for orthopedic and dental implants, especially in osteoporotic subjects. In this study, a new dual-controlled, local, bone-targeting delivery system was successfully constructed by loading tetracycline-grafted simvastatin (SV)-loaded polymeric micelles in t...

Dental Implant Design and Biological Effects on Bone-Implant Interface

Although dental implants have become a predictable aspect of tooth replacement in prosthodontic treatment [1, 2, 3, 4, 5, 6], failures of up to 10% are still encountered. Furthermore these failures have been more associated with “soft” bone quality [7], 1985) such as encountered in the maxillary posterior area [8, 9, 10, 11, 12]. In a review article by Esposito et al [13], bone quality and volu...

Bone implant interface, osteolysis and potential therapies.

Titania nanotubes for orchestrating osteogenesis at the bone-implant interface.

Titanium implants can fail due to inappropriate biomechanics at the bone-implant interface that leads to suboptimal osseointegration. Titania nanotubes (TNTs) fabricated on Ti implants by the electrochemical process have emerged as a promising modification strategy to facilitate osseointegration. TNTs enable augmentation of bone cell functions at the bone-implant interface and can be tailored t...